Vaping FAQs

what are the effects of vaping on lungs journal article

by Mr. Mervin Thompson III Published 2 years ago Updated 1 year ago
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Harmful Effects of Vaping

  • 1. Nicotine-related effects So far, scientists know that e-cigarettes commonly contain nicotine, which in itself has known side effects such as addiction, toxicity to a developing fetus, cancer, impaired adolescent brain development, etc.
  • 2. Lung damage Vaping is associated with acute and chronic cough, bronchitis, pneumonia, EVALI, and lung injury.
  • 3. Bad for oral health

Full Answer

Does vaping harm your lungs?

“Vaping involves inhaling a vapor produced by an e-cigarette device deep into your lungs. Vaping devices contain an oil, often called vape juice, to which nicotine and any number of potentially harmful chemicals are added for flavoring or to create a certain aroma, like cotton candy or blueberry. Vape liquids can do irreparable harm to the lungs and other parts of the body.”

What are the long term side effects of vaping?

  • Respiratory problems like asthma
  • Heart attacks
  • Reproductive issues
  • Low birth weight for babies when mothers vape during pregnancy
  • Irritation of eyes and airways 2
  • Poor brain development
  • Infections
  • Seizures
  • Lung disease problems like popcorn lung & EVALI 3

How does vaping affect your lungs?

Vaping-related lipoid pneumonia is the result of inhaling oily substances found in e-liquid, which sparks an inflammatory response in the lungs. Symptoms of lipoid pneumonia include: Chronic cough. Shortness of breath. Coughing up blood or blood-tinged mucus.

What are the dangers of vaping?

The interchangeable use of smoking and vaping is most common in people under age 35. They face equal risk of heart attack or stroke than if they lit up exclusively. The takeaway is that there is no ‘best’ method of inhaling nicotine.

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What are the effects of vaping on lungs?

Vaping and Popcorn Lung Diacetyl is frequently added to flavored e-liquid to enhance the taste. Inhaling diacetyl causes inflammation and may lead to permanent scarring in the smallest branches of the airways — popcorn lung — which makes breathing difficult. Popcorn lung has no lasting treatment.

What are 3 harmful effects of vaping?

Side effects of vapingcoughing.dry mouth and throat.shortness of breath.mouth and throat irritation.headaches.

What are 5 risks of vaping?

Vaping has been linked to lung injury.Rapid onset of coughing.Breathing difficulties.Weight loss.Nausea and vomiting.Diarrhea.

Does vaping increase risk of lung disease?

E-cigarettes produce a number of dangerous chemicals including acetaldehyde, acrolein, and formaldehyde. These aldehydes can cause lung disease, as well as cardiovascular (heart) disease.

What are 10 dangers of vaping?

Serious & Potentially Long-Term Effects of VapingNicotine addiction.Severe lung injury.Seizures.Cryptogenic organizing pneumonia (COP), formerly known as idiopathic bronchiolitis obliterans with organizing pneumonia (BOOP)Popcorn lung.Strokes.Heart attacks.

Is vape worse than cigarettes?

1: Vaping is less harmful than smoking, but it's still not safe. E-cigarettes heat nicotine (extracted from tobacco), flavorings and other chemicals to create an aerosol that you inhale. Regular tobacco cigarettes contain 7,000 chemicals, many of which are toxic.

What are the benefits of vape?

Benefits of vaping Vaping can help some people quit smoking. Vaping is usually cheaper than smoking. Vaping is not harmless, but it is much less harmful than smoking. Vaping is less harmful to those around you than smoking, as there's no current evidence that second-hand vapour is dangerous to others.

How many kids are vaping?

2022 Findings on Youth E-Cigarette Use 14.1% (2.14 million) of high school students and 3.3% (380,000) of middle school students reported current e-cigarette use.

How safe is vaping?

Vaping is not completely risk-free, but it poses a small fraction of the risk of smoking cigarettes. The long-term risks of vaping are not yet clear. E-cigarettes do not produce tar or carbon monoxide, two of the most harmful elements in tobacco smoke.

How long does vaping take to damage lungs?

Exposure for just three days was enough to incur sufficient damage to their lungs, setting the stage for long-term chronic lung damage.

Which is better for lungs vaping or smoking?

A: Overall, there's not much difference between smoking and vaping. Commonly, smoking was thought to be more harmful because the product is being burnt and smoke inhaled into the lungs. But we're finding very similar damage from heating up vaping solutions and inhaling that vapor into the lungs.

Can vaping cause collapsed lung?

Typically, the blisters are not problematic. But both vaping and smoking increase the risk of bursting which can lead to lung collapse. Signs of a collapsed lung include sharp chest or shoulder pain, shortness of breath and difficulty breathing.

Why do teenagers vape?

addiction, they like the “hit” they get from nicotine. appealing flavors (e.g. fruit, candy, dessert) devices are seen as trendy, or a status symbol. they consider vaping “harmless” and “safer than smoking” in order to quit or cut down on smoking.

Is vaping without nicotine harmful?

Some vape product manufacturers claim that vaping is a completely safe alternative to smoking. However, early research into the safety of the practice suggests this is not the case. In fact, it appears that vaping, even without nicotine, can have harmful effects on the body.

Can vaping make you sick?

Symptoms of vaping-related illness are very similar to symptoms that we see with illnesses such as pneumonia, cold, and flu. Symptoms could be a cough, shortness of breath, potentially difficulty breathing as well as nausea and vomiting. These symptoms can happen over a couple of days or they can appear quickly.

Can vaping make you lose weight?

In short, no, vaping does not help you lose weight. Although E-Liquids contain nicotine that can suppress your appetite, it does not actively take part in helping someone lose weight. But, in the event a smoker looking to quit cigarettes, chooses to swap vaping, they may notice that it helps them maintain their weight.

What is the difference between evali and lipoid pneumonia?

a, bThe histologic distinction between exogenous lipoid pneumonia and electronic cigarette or vaping-associated lung injury (EVALI) is dramatic and distinctive. Exogenous lipoid pneumonia shows numerous lipid vacuoles a, most of which are much larger than individual cells. There is associated fibrosis in which many of the droplets are embedded. Occasional macrophages contain lipid droplets within their cytoplasm. However, the droplets are much larger and more variable (arrow) compared to EVALI, H&E, × 100. Larger lipid vacuoles are surrounded by several multinucleated giant cells and a foreign body giant cell reaction (arrowhead) b, a feature not seen in EVALI, H&E, × 200

What stains are used for ALI?

All cases of ALI, regardless of the pathologic pattern, should include testing for infectious organisms with acid-fast bacilli and Grocott’s methenamine silver (GMS) stains at a minimum. If there is significant necrosis and neutrophilic inflammation, viral immunohistochemistry may also be considered (cytomegalovirus, herpes virus, adenovirus). Oil red-O does not have a clear role in the histologic assessment and work-up of lung specimens, especially considering that fresh, unprocessed tissue must be used for effective Oil red-O. Despite the low sensitivity and specificity of Oil red-O, it remains on many clinical algorithms [30] for the pathologic work-up suspected EVALI. However, given its lack of utility, Oil red-O is not necessary for diagnostic purposes in suspected EVALI cases, cytology or surgical pathology specimens.

What is the term for the accumulation of endogenous cellular lipid material from epithelial injury?

The fine cytoplasmic vacuoles encountered in the macrophages actually represent the accumulation of endogenous cellular lipid material from epithelial injury, a process referred to as endogenous lipoid pneumonia. Endogenous lipoid pneumonia is seen in a variety of settings including acute lung injury, obstructed airways, and infections [23–25].

How long does it take for eli to show up?

Symptoms occur anywhere from hours to weeks prior to presentation. Laboratory tests commonly reveal an elevated erythrocyte sedimentation rate and c-reactive protein level, transaminitis, and leukocytosis [13]. To meet the CDC criteria for a “confirmed” EVALI case, patients must have vaped within 90 days before symptom onset, have bilateral infiltrates on chest imaging, have a negative evaluation for infection, and have no other plausible alternative diagnoses. Cases of “Probable” EVALI share similar criteria, except that infection may be present, but the clinical team caring for the patient has high confidence that infection is not the primary cause for the patient’s respiratory condition.

What is an end vape?

ENDS, also known as E-cigarettes and vaping devices, were originally developed as a replacement device for conventional tobacco cigarette smokers [1]. However, their success in the arena of smoking cessation has been very limited, and they remain unapproved as cessation tools due to a lack of data demonstrating efficacy relative to currently approved nicotine replacement therapies [2]. The aerosols produced by E-cigarettes are known to cause a variety of deleterious health effects, although more research and long-term studies are still needed [2]. E-devices have rapidly evolved since entering the international market in 2013, with vape pens, box mods, and pod-based devices being the most commonly used vaping devices in 2020 [3]. Although E-cigarettes are used in conjunction with conventional tobacco by many cigarette smokers (dual users), their sole use in young adults and adolescents has skyrocketed [4]. This is concerning as use of tobacco products had been declining worldwide for over 50 years, and now, a new generation of nicotine addicts is being created through these novel vaping devices through the use of appealing flavors and packaging [5]. Even more concerning is that children and teenagers who use E-cigarettes are more likely to smoke conventional tobacco [6].

What is giant cell interstitial pneumonia?

Rare descriptions of additional patterns of lung injury have been described, including giant cell interstitial pneumonia that is a form of pneumoconiosis related to hard metal exposure and shows the accumulation of numerous multinucleated giant cells within the air spaces.

Is lipoid pneumonia a pathologic disease?

Despite the published reports of lipoid pneumonia as a mechanism of injury in EVALI, no well-characterized radiologic and pathologic cases have been published. Most of the clinicopathologic diagnoses of lipoid pneumonia have been based on the finding of lipid-laden macrophages in BAL cytology specimens (discussed in detail below). To date, there have been no HRCT features of classic exogenous lipoid pneumonia, specifically the demonstration of macroscopic fat on HRCT, described in the literature.

What are the effects of smoking?

The recent tragic and alarming cases of severe lung disease are clearly cause for concern. A number of other health effects are also worrisome: 1 Nicotine is highly addictive and can affect the developing brain, potentially harming teens and young adults. Even some "nicotine-free" e-cigarettes have been found to contain nicotine. 2 Some substances found in e-cigarette vapor have been linked to an increased risk of cancer. 3 Teens who vape are more likely to begin smoking cigarettes. 4 Explosions and burns have been reported with e-cigarettes while recharging the devices, due to defective batteries. 5 Accidental exposure to liquid from e-cigarettes has caused acute nicotine poisoning in children and adults. 6 Vaping during pregnancy could harm a developing fetus.

What are the chemicals in e-cigarettes?

E-cigarettes produce a number of dangerous chemicals including acetaldehyde, acrolein, and formaldehyde. These aldehydes can cause lung disease, as well as cardiovascular (heart) disease. Electronic cigarettes, or e-cigarettes, put nicotine into your lungs and bloodstream.

Is vaping safe for pregnant women?

The CDC’s position is that "E-cigarettes have the potential to benefit adult smokers who are not pregnant if used as a complete substitute for regular cigarettes and other smoked tobacco products." Meanwhile, the FDA warns that vaping is "not safe for youth, young adults, pregnant women, or adults who do not currently use tobacco products."

How many puffs can you have with vaping?

With vaping, you can have one or two puffs, be satisfied, and be done whenever you want. You are not committed. You might only need one puff, then maybe five minutes later you take another one. You won’t overdo because your brain will never have to justify it as an expense if you stop now. You just stop now.

How much ohm is toxic?

It is likely that the super-heating of e-liquids that takes place in an RBA run at less than 1 oh m will create some toxic materials.

What are the symptoms of vapors?

Typically, symptoms have started gradually, with shortness of breath and/or chest pain before more severe breathing difficulty led to hospital admission.

How many people have lung disease from e-cigarettes?

According to the CDC: Nearly 200 e-cigarette users have developed severe lung disease in 22 states (and the numbers keep rising — a Washington Post story put the number at 354). Most cases were among teens and young adults.

What is an e-cigarette?

This raises significant health concerns [1]. Simply put, electronic cigarettes (e-cigarettes) are electronic devices designed to vaporize chemical compounds. These devices have different components, including a mouthpiece, a liquid tank, a heating element, and a battery [2]. They come in various shapes, sizes, and device types, and are known by different names to different users. The most common terminologies include e-cigs, vapes, e-hookahs, vape pens, mods, tanks, or electronic nicotine delivery systems (ENDS). The process of using the devices is sometimes referred to as vaping or juuling, the latter so named for the particular device brand [3].

What are the health risks of smoking e-cigarettes?

The device is made up of a mouthpiece, liquid tank, a heating element, and a battery. E-cigarette use may pose health risks in the form of cardiovascular and respiratory diseases. These health risks have implications to not only the primary user, but the aerosols can also cause secondhand and thirdhand injuries to others in the vicinity. Acute lung injury may also be associated with the use of e-cigarettes, but the underlying cause remains unknown. Clinicians, including hospitalists, pulmonologists, intensivists, medical examiners, pathologists, and the like, should report possible cases as the medical community continues to assess the health risks of e-cigarette use.

What are the symptoms of e-cigarette use?

Most of the patients in their study presented with shortness of breath, cough, and chest pain [12]. The severity of the illness varied from mild shortness of breath requiring oxygen supplementation via nasal cannula to severe debilitating respiratory failure requiring intubation and mechanical ventilation [12,13]. Five patients identified in July and August 2019 had acute lung injury associated with e-cigarette use. These patients were identified in two different hospitals in North Carolina, all were admitted for hypoxemic respiratory failure. All the patients reported a history of recent e-cigarette use. They were initially admitted for community-acquired pneumonia (CAP), but their symptoms worsened with conventional treatment for CAP. They were eventually diagnosed with acute exogenous lipoid pneumonia [13]. Another patient had presented with shortness of breath; investigations yielded a diagnosis of spontaneous pneumothorax. An 18-year-old patient had no history of cigarette smoking but endorsed daily use of e-cigarettes. The patient then had a recurrent spontaneous pneumothorax. He had no significant medical or surgical history to increase his propensity for spontaneous pneumothorax [14].

Why is it important to understand the nature and attitude of e-cigarettes use among young adults?

Understanding the nature and attitude of e-cigarettes use among young adults is very important as this is the period when they transition into social contexts (e.g., college, peer pressure, and workplace) often resulting in an increased prevalence in substance use and the development of addictive patterns [18] .  This raises a public health concern as it suggests that the younger generations of users, which have the highest rates of electronic cigarettes use, might become addicted to these devices despite unknown long-term physiologic and pathologic consequences [19].

Is vaping associated with pulmonary disease?

So far, most of the literature on vaping-associated pulmonary disease we have are case reports and case series. A high index of suspicion is paramount as there are reports of patients that rapidly progressed to acute respiratory failure requiring intubation and mechanical ventilation [3]. The use of ENDS continues to grow in the United States. For example, while the use of combustible tobacco cigarettes has declined significantly, the United States ENDS market now exceeds 8 billion dollars [4]. At the moment, there are regular advertisements for e-cigarettes, promoting them as viable and safe alternatives to cigarettes smoking despite an absence of any studies to prove superior efficacy to conventional smoking cessation strategies already studied, such as nicotine replacement, bupropion hydrochloride, varenicline, and counseling [5]. E-cigarettes use may pose health risks in the form of cardiovascular and respiratory diseases. Tobacco cigarette smoking is the primary cause of preventable cardiovascular death in the United States, and smoking cessation has long been the focus of significant public health efforts. The rates of tobacco smoking in the United States have continued to decline and reached historic lows according to a Surgeon General report in 2014. However, with this decline, the use of electronic cigarettes, introduced in 2007, has markedly increased, especially among young people [6]. Healthcare providers should be on the alert for symptoms suggestive of acute lung injury secondary to vaping and remind patients that even though some e-cigarettes contain nicotine, they are currently not approved by the Food and Drug Administration as a cessation aid for smokers. Clinicians, including hospitalists, pulmonologists, medical examiners, primary care physicians, pathologists, and the like, are reminded to report possible cases [3,7].  People should consider not using e-cigarettes. This is especially the case for high-risk groups, including those without prior experiences, teenagers, pregnant women/nursing mothers, or adults who do not currently use oral tobacco products. These health risks have implications to not only the primary user, but the aerosols can also cause secondhand and thirdhand injuries to others in the vicinity. However, the regulations for public e-cigarette use vary across states and are inconsistent across cities within certain states. These variations in restrictions exist in both locations and types of product use, public versus private use, and types of products allowed in certain places [7]. Consumers in most states must be 18 years or older to purchase the device, although underage sales have been reported in retailers and online. The Food and Drug Administration has expressed concerns that certain flavored e-cigarettes are appealing to youth who may be unaware of the products’ addictiveness and some others who may have never tried a nicotine product [8]. There are many compounds in the aerosols and liquids and the selling point mostly used is that it can serve as a “Healthier” alternative to tobacco smoking even though the Food and Drug Administration has not approved this. The American Cancer Society discourages the dual use of electronic cigarettes and cigarettes because such use has not resulted in reduced exposures to the harmful effects of smoking [9,10]. Flavoring was considered by most users as the most important reason for vaping [10].  Over the past year, the Center for Disease Control has drawn attention to severe pulmonary disease associated with the use of electronic cigarette products. There have been reports of more than 200 cases associated with the use of these devices, using both known and unknown products [11]. The exact cause of these findings is still uncertain. Available data have been either case reports or case series. Some of the reported cases of e-cigarette-associated pulmonary illnesses include spontaneous pneumothorax, acute eosinophilic pneumonia, respiratory bronchiolitis-associated interstitial lung disease, hypersensitivity pneumonitis, organizing pneumonia, and acute exogenous lipoid pneumonia [12-14].

Does vaping cause ground glass opacities?

Chest computed tomography scans obtained from patients with vaping-associated lung disease showed significant findings. Ground-glass opacities seem to be a common finding in the imaging studies of most patients with e-cigarette-associated lung disease [16,17].

What are vaping devices?

Vaping devices, also known as e-cigarettes, vape pens, and e-hookahs among other terms, come in many shapes and sizes. Some look like traditional cigarettes, cigars, or pipes. Others are shaped like every-day objects, such as pens or USB memory sticks.

What chemicals are in vaping?

Vaping exposes the lungs to a variety of chemicals. These may include the main active chemicals in tobacco (nicotine) or marijuana (THC), flavorants, and other ingredients that are added to vaping liquids. Plus, other chemicals can be produced during the vaporizing process.

How old do you have to be to vape?

New laws are aimed at curbing vaping among teens. People must now be 21 to buy any tobacco product, including vaping products. And companies can no longer produce and sell flavors that appeal to children like fruit and mint. If you’ve already started vaping or smoking cigarettes, it’s never too late to quit.

How does puffing work?

While they may look different, most vaping devices work in a similar way. Puffing activates a battery-powered heating device. This heats the liquid in a cartridge, turning it into vapors that are inhaled.

Is vaping more popular in high school?

Vaping is now more popular among teens than smoking traditional cigarettes. One in four high school seniors say they vaped nicotine in the past month. And studies have found that teens who vape nicotine may be more likely to go on to smoke traditional cigarettes.

Can nicotine be inhaled in a vaporizer?

Plus, other chemicals can be produced during the vaporizing process. “If the liquid has nicotine in it, then the user is inhaling nicotine along with the other ingredients in the liquid,” explains Dr. Thomas Eissenberg, an expert on tobacco research at Virginia Commonwealth University.

Is vaping harmful?

So how safe is vaping? Studies suggest nicotine vaping may be less harmful than traditional cigarettes when people who regularly smoke switch to them as a complete replacement. But nicotine vaping could still damage your health.

Why is vaping so successful?

Vaping is more success full than other methods because it also mimics (mimics, not reality) other parts of the smoking "experience.". You're inhaling. It has a flavor. It produces what looks like, but isn't, smoke.

Does vaping help with smoking?

ACSH has previously reported that vaping very likely helps smokers quit cigarettes, and maybe even nicotine, for good. Citing some of the same literature we have, Barton reached a similar conclusion about smoking cessation. While acknowledging the limitations of these studies ( discussed here ), she explained:

Is vaping safe for 2021?

By Cameron English — May 25, 2021. Despite increasing evidence that vaping is safer than smoking, uncertainty surrounds the long-term effects of electronic cigarette use. Many in the tobacco control field have used the lack of data to speculate about these unknown risks.

Is vaping bad for you?

After contrasting the overall risk of vaping with smoking, Barton added that some preliminary studies have indeed associated e-cigarette use with various negative outcomes. For example, an onslaught of headlines in mid-2019 warned the public about an outbreak of “e-cigarette or vaping product use-associated lung injury” (EVALI). Under-reported at the time was the fact that the injury-causing devices were typically purchased illegally and contained THC or certain dangerous additives, which made them far more harmful than the nicotine-containing devices adult customers can legally purchase in licensed vape shops in the US and UK. Surveying the literature nearly two years later, we get a better sense of the problem:

Is nicotine replacement a tobacco product?

According to Nicotine and Tobacco Research, "If all products containing nicotine derived from tobacco were labeled as 'tobacco products' internationally, then nicotine-replacement therapies would be classified as tobacco products, which they are clearly not.".

Can you buy THC in vape shops?

Under-reported at the time was the fact that the injury-causing devices were typically purchased illegally and contained THC or certain dangerous additives, which made them far more harmful than the nicotine-containing devices adult customers can legally purchase in licensed vape shops in the US and UK.

Is vaping better than smoking?

Compared to the typical news report about vaping —"Vaping is not better than smoking, and it still causes long-term lung damage"—Barton's article illustrated how we should talk about scientific issues when the evidence surrounding them is evolving. Let's consider a few examples.

What is the e-cigarette outbreak?

More recently, in August 2019, the US Centers for Disease Control and Prevention (CDC) declared an outbreak of the e-cigarette or vaping product use-associated lung injury (EVALI) which caused several deaths in young population (reviewed in [ 20 ]).

What is the nicotine content of e-liquid?

The concentrations range from 0 (0%, nicotine-free option) to 20 mg/mL (2.0%)—the maximum nicotine threshold according to directive 2014/40/EU of the European Parliament and the European Union Council [ 33, 34 ]. Despite this normative, however, some commercial e-liquids have nicotine concentrations close to 54 mg/mL [ 35 ], much higher than the limits established by the European Union.

How much nicotine is in a cigarette?

Assuming that a conventional cigarette contains 0.172–1.702 mg of nicotine [ 51 ], the daily nicotine dose administered to these animals corresponds to 40–400 cigarettes for a 70 kg-adult, which is a dose of an extremely heavy smoker.

What is an ENDS device?

Electronic nicotine dispensing systems (ENDS), commonly known as electronic cigarettes or e-cigarettes, have been popularly considered a less harmful alternative to conventional cigarette smoking since they first appeared on the market more than a decade ago. E-cigarettes are electronic devices, essentially consisting of a cartridge, filled with an e-liquid, a heating element/atomiser necessary to heat the e-liquid to create a vapour that can be inhaled through a mouthpiece, and a rechargeable battery (Fig. 1) [ 1, 2 ]. Both the electronic devices and the different e-liquids are easily available in shops or online stores.

What are the components of e-liquid?

The most common and major components of e-liquids are PG or 1,2-propanediol, and glycerol or glycerine (propane-1 ,2,3-triol). Both types of compounds are used as humectants to prevent the e-liquid from drying out [ 2, 53] and are classified by the Food and Drug Administration (FDA) as “Generally Recognised as Safe” [ 54 ]. In fact, they are widely used as alimentary and pharmaceutical products [ 2 ]. In an analysis of 54 commercially available e-liquids, PG and glycerol were detected in almost all samples at concentrations ranging from 0.4% to 98% (average 57%) and from 0.3% to 95% (average 37%), respectively [ 35 ].

What is an e-cigarette?

E-cigarettes are electronic devices, essentially consist ing of a cartridge, filled with an e-liquid, a heating element/atomiser necessary to heat the e-liquid to create a vapour that can be inhaled through a mouthpiece, and a rechargeable battery (Fig. 1) [ 1, 2 ].

How does heating affect aerosols?

Several compounds detected in e-cigarette aerosols are not present in e-liquid s and the device material also seems to contribute to the presence of metal and silicate particles in the aerosols. The heat ing conditions especially on humectants, flavourings and the low-quality material used have been identified as the generator of the new compounds in aerosols. Some compounds generated from humectants (propylene glycol and glycerol) and flavourings, have been associated with clear airways impact, inflammation, impairment of cardiovascular function and toxicity. In addition, some of them are carcinogens or potential carcinogens

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