is vaping a gateway to smoking reddit

Is vaping nicotine a gateway to smoking?

We have always said that vaping nicotine is a gateway or path to smoking cessation. Much of the current vaping concerns suggest that it is a gateway in the other direction to smoking cigarettes; a new paper in Nicotine and Tobacco Research looks at the possibility.

Is vaping a gateway to smoking among adolescents?

Is vaping a gateway to smoking: a review of the longitudinal studies This review highlights the strong evidence that not only are ECs are not an effective tool for smoking cessation among adolescents, they actually are associated with higher incidence of combustible cigarette smoking.

Is vaping nicotine bad for You?

Using nicotine habitually is a bad idea. It is worse when delivered by combustion, with fewer health consequences when vaporized. We have always said that vaping nicotine is a gateway or path to smoking cessation.

Will vaping cause the next smoking epidemic?

Blaha says there’s evidence that young people who vape are more likely to go on to use illicit drugs and tobacco products such as cigarettes. “We might be causing the next smoking epidemic through young people getting addicted to electronic cigarettes early in life,” he says.

How many times more likely is an e-cigarette smoker to smoke?

An ever e-cigarette smoker was 17 times more likely to have tried conventional cigarettes, and 35 times more likely to be a current smoker. A current e-cigarette user was 22 times more likely to have tried traditional smoking and 16 times more likely to be currently smoking.

What does "favourite" mean in Disqus?

Favoriting means this is a discussion worth sharing. It gets shared to your followers' Disqus feeds, and gives the creator kudos!

How long does a Juul pod last?

I'd usually make a pack last me three or four days. But one JUUL pod, which supposedly is the equivalent of a pack of cigarettes, will last me at least five days.

Is vaping harmful to smokers?

But CDC, FDA and Big Pharma funded CTFK, ACS, AHA, ALA, AMA, etc, refuse to acknowledge these facts, and continue to falsely claim vaping is a gateway to cigarettes, doesn't help smokers quit, may be more harmful than cigarettes, and should not be done by anyone (including smokers and vapers) in order to achieve their lobbying goal of banning sales of virtually all nicotine vapor products, which will protect cigarette markets.

Is Juul better than smoking?

No one ever thought that nicotine was GOOD for you, but JUUL has been better for me than traditional smoking.

Is e-cigarette smoking bad for you?

E-cigarettes are not a gateway as much as they may be an alternative path. As a physician and father, there is little difference between gate and path; using nicotine habitually is just stupid and bad for your health. But wearing the hat of population health, e-cigarette use seems to be a better alternative to conventional cigarettes.

Is e-cigarette use better than conventional cigarettes?

But wearing the hat of population health, e-cigarette use seems to be a better alternative to conventional cigarettes. The study has limitations. First, it is a statistical conclusion, not a randomized control study.

Is Blaha concerned about vaping?

In addition to nicotine, artificial flavorings and other chemicals that users inhale, Blaha is concerned about some of the behavioral aspects of vaping.

Is vape juice a tobacco product?

As of 2016, the Food and Drug Administration (FDA) classifies e-cigarettes and nicotine-laced vape juice as tobacco products and regulates them accordingly.

Is vaping a habit?

Nicotine in any form is highly addictive. Vaping, using nicotine-laced products, can become a tenacious and expensive habit, and kids might not stop there. Blaha says there’s evidence that young people who vape are more likely to go on to use illicit drugs and tobacco products such as cigarettes.

Is it safe to smoke electronic cigarettes?

Smoking electronic cigarettes is often considered safer than regular smoking. Learn why vaping is still harmful, and why you should rethink taking it up.

Is vaping harmful to kids?

Blaha says that while the FDA has recently taken a stance that is more toward what it calls “modified risk” tobacco products that cause less harm than smoking, vaping is certainly more harmful than not using anything at all. “Kids have such a poor understanding of vaping products — it’s extraordinary,” he says.

Why do people use vaping?

The use of e-cigarettes, called vaping, was initially promoted to help people stop smoking, however, is currently also associated with alternative user motives, attractiveness to young people, split-risk approaches and divergent legislation.

What is Juul e-cigarette?

"Pod-based" e -cigarettes such as JUUL are currently the most prevalent electronic nicotine delivery systems (ENDS) in the United States. JUUL-type ENDS utilize nicotine salts protonated with benzoic acid rather than freebase nicotine. However, limited information is available on the cellular effects of these products. Cytoplasmic Ca2+ is a universal second messenger that controls many cellular functions including cell growth and cell death. Of note, dysregulation of cell Ca2+ homeostasis has been linked with several disease processes including autoimmune disease and several types of cancer. We exposed HEK293T cells and THP-1 macrophage-like cells to different JUUL e-liquids. We evaluated their effects on cellular viability and Ca2+ signaling by measuring fluorescence from calcein-AM/propidium iodide and Fluo-4, respectively. E-liquid autofluorescence was used to look for e-liquid permeation into cells. To identify the mechanisms behind the Ca2+ responses, different inhibitors of Ca2+ channels and phospholipase C signaling were used. JUUL e-liquids caused significant cytotoxic effects, with "Mint" flavor being the most cytotoxic. The Mint flavored e-liquid also caused a significant elevation in cytoplasmic Ca2+ . Using autofluorescence, the permeation of JUUL e-liquids into live cells was confirmed, indicating that intracellular organelles are directly exposed to e-liquids. Further studies identified the endoplasmic reticulum as being the source of e-liquid-induced changes in cytoplasmic Ca2+ . Nicotine salt-based e-liquids cause cytotoxicity and elevate cytoplasmic Ca2+ , indicating that they can exert biological effects beyond what would be expected with nicotine alone. These effects are flavor-dependent, and we propose that flavored e-liquids be reassessed for potential lung toxicity.

What are the genes that are involved in nicotine addiction?

They highlight coding and synonymous polymorphisms in a cluster on chromosome 15, encompassing the CHRNA5, CHRNA3 and CHRNB4 genes, coding for three subunits of the nicotinic acetylcholine receptor (nAChR). They have inspired an important number of preclinical studies, and will hopefully lead to the definition of novel drug targets for treating NA. Here, we review these candidate gene and genome-wide association studies (GWAS) and their direct implication in human brain function and NA-related phenotypes. We continue with a description of preclinical work in transgenic rodents that has led to a mechanistic understanding of several of the genetic hits. We also highlight important issues with regards to CHRNA3 and CHRNB4 where we are still lacking a dissection of their role in NA, including even in preclinical models. We further emphasize the use of human induced pluripotent stem cell-derived models for the analysis of synonymous and intronic variants on a human genomic background. Finally, we indicate potential avenues to further our understanding of the role of this human genetic variation. This article is part of the special issue on ‘Contemporary Advances in Nicotine Neuropharmacology’.

Is vaping increasing?

Vaping has been increasing with Monitoring the Future, indicating nicotine vaping (2017–2018) having the largest single-year jump among any substance recorded in its 45-year history. Overall, research on vaping has been substantially limited, primarily in the context of vaping and delinquency. This study’s purpose is to examine how nicotine vaping compares with other common substances used by adolescents like alcohol and cigarettes within the context of delinquency. Using secondary data from Monitoring the Future: A Continuing Study of the Lifestyles and Values of Youth conducted in 2017, with a sample size of 8,467 participants, we find that ever-nicotine “vapers” were associated with less delinquency than ever-cigarette-using youth; however, these “vapers” were associated with more delinquency than ever-alcohol users. We interpret these results in the context of social bonding and social learning theory and policies to create awareness on the potential social implications of vaping.