Vaping FAQs

can vaping cause pulmonary edema

by Savion Will Published 2 years ago Updated 1 year ago

Pulmonary edema, most likely secondary to diffuse alveolar hemorrhage, is a known complication of e-cigarette use.Jun 30, 2020

Full Answer

Can vaping cause edema?

Dehydration can cause edema and vaping dehydrates you pretty bad. I can't say that's your issue but it was for me when I started. I never took a diuretic or anything but until I upped my fluid intake my ankles and hands would swell a lot especially if I was in the sun a lot. Yep, I retain water too. I drink about 6 to 8 bottles of water a day.

Can vaping cause lung injuries?

In light of this outbreak that is characterized clearly by a chemically induced acute lung injury, continued efforts should be made to increase public awareness of the harmful effect of vaping. Physicians should discourage their patients from vaping products that contain THC.

Can vaping vitamin E acetate cause lung injury?

Additional experimental studies in animals may provide information on whether exposure to vitamin E acetate alone can directly cause acute lung injury. The focus of the outbreak has now turned to vaping products that contain THC, but it is important not to lose sight of the larger health issues around vaping.

Is vaping-induced respiratory distress related to e-cigarette use?

Two letters also published in the Journal add further support to vaping-induced respiratory distress: a six-case cluster from Utah 4 and a report of imaging changes seen in a range of cases. 5 The syndrome has been termed by the Centers for Disease Control and Prevention (CDC) as e-cigarette, or vaping, product use–associated lung injury (EVALI).

How can vaping lead to a pulmonary embolism?

A pulmonary embolism is an obstruction of one of the pulmonary arteries of your lungs and can be fatal. These blockages are caused by clumps of material, most often blood clots, that travel to the lungs from other parts of the body. The creation of this barrier in the artery stops blood from flowing to that part of the lung, which can lead to a pulmonary infarction or death of the lung tissue.

What causes a pulmonary infarction?

The creation of this barrier in the artery stops blood from flowing to that part of the lung, which can lead to a pulmonary infarction or death of the lung tissue. There are many factors that can influence blood clotting activity, including smoking and vaping.

What happened to Juul?

A 24-year-old Rochester man filed a lawsuit against JUUL in September 2019, after being diagnosed with pulmonary embolism that same March. He stated that JUUL falsely portrayed its product as a safe alternative to cigarettes, which prompted him to start using the device to help him quit chewing tobacco.

Does smoking make blood clots?

Smoking can make your blood cells “sticker” and easier to clump together, as well as harming the lining of blood vessels which can make it easier for clots to form. Older individuals more commonly suffer from pulmonary embolisms, but vaping is changing that.

Is vaping harmful?

The Dangers of Vaping. It is now known that using e-cigarette products like JUUL can be just as detrimental as smoking traditional cigarettes, if not more. If you or a loved one experienced a pulmonary embolism after vaping, contact the accomplished attorneys at Kwartler Manus, LLC to schedule a consultation.

What is an end vape?

ENDS, also known as E-cigarettes and vaping devices, were originally developed as a replacement device for conventional tobacco cigarette smokers [1]. However, their success in the arena of smoking cessation has been very limited, and they remain unapproved as cessation tools due to a lack of data demonstrating efficacy relative to currently approved nicotine replacement therapies [2]. The aerosols produced by E-cigarettes are known to cause a variety of deleterious health effects, although more research and long-term studies are still needed [2]. E-devices have rapidly evolved since entering the international market in 2013, with vape pens, box mods, and pod-based devices being the most commonly used vaping devices in 2020 [3]. Although E-cigarettes are used in conjunction with conventional tobacco by many cigarette smokers (dual users), their sole use in young adults and adolescents has skyrocketed [4]. This is concerning as use of tobacco products had been declining worldwide for over 50 years, and now, a new generation of nicotine addicts is being created through these novel vaping devices through the use of appealing flavors and packaging [5]. Even more concerning is that children and teenagers who use E-cigarettes are more likely to smoke conventional tobacco [6].

What is the difference between evali and lipoid pneumonia?

a, bThe histologic distinction between exogenous lipoid pneumonia and electronic cigarette or vaping-associated lung injury (EVALI) is dramatic and distinctive. Exogenous lipoid pneumonia shows numerous lipid vacuoles a, most of which are much larger than individual cells. There is associated fibrosis in which many of the droplets are embedded. Occasional macrophages contain lipid droplets within their cytoplasm. However, the droplets are much larger and more variable (arrow) compared to EVALI, H&E, × 100. Larger lipid vacuoles are surrounded by several multinucleated giant cells and a foreign body giant cell reaction (arrowhead) b, a feature not seen in EVALI, H&E, × 200

Is vaping a respiratory disease?

In the summer of 2019, an acute, mysterious, and deadly respiratory illness related to vaping emerged, primarily in young patients, in the USA. Cases increased dramatically and peaked in late September 2019. The Center for Disease Control and Prevention (CDC) termed the disease causing this epidemic E-cigarette or vaping product use-associated lung injury (EVALI). Prior to EVALI, vaping had been associated with a variety of different pulmonary presentations ranging from lipoid pneumonia to diffuse alveolar hemorrhage, but at low numbers. In this review, we discuss electronic nicotine delivery systems (ENDS) as well as the etiology, clinical presentation, imaging findings, pathologic features, treatment, and long-term consequences of EVALI. We conclude with a discussion on the practical impact EVALI has had on the practice of pathology.

Is vaping a lung disease?

Although lung diseases caused by vaping have been reported since the modern invention of the electronic cigarette , in the summer of 2019, patients began to present to health care centers at epidemic levels with an acute respiratory illness relating to vaping, which the Center for Disease Control termed E-cigarette or vaping product use-associated lung injury (EVALI). This review discusses electronic nicotine delivery systems as well as the etiology, clinical presentation, imaging findings, pathologic features, treatment, and long-term consequences of EVALI. We conclude with the practical impact EVALI has had on the practice of pathology.

Is lipoid pneumonia a pathologic disease?

Despite the published reports of lipoid pneumonia as a mechanism of injury in EVALI, no well-characterized radiologic and pathologic cases have been published. Most of the clinicopathologic diagnoses of lipoid pneumonia have been based on the finding of lipid-laden macrophages in BAL cytology specimens (discussed in detail below). To date, there have been no HRCT features of classic exogenous lipoid pneumonia, specifically the demonstration of macroscopic fat on HRCT, described in the literature.

What is toxic inhalation pneumonitis?

Indeed, emergency response guidelines for medical personnel describe toxic inhalation pneumonitis as a heterogeneous group of chemically induced injuries to the lung parenchyma as well as to the upper respiratory tract.

What are the symptoms of a chemical inhaler?

Depending on the type of chemical agent and the amount of material inhaled, patients may experience symptoms ranging from minor respiratory tract discomfort to acute airway injury and damage to the parenchyma with pneumonitis, alveolar edema, respiratory failure, and death.

How many people will be hospitalized with evali in 2020?

The CDC reported that as of January 21, 2020, a total of 2711 patients had been hospitalized with EVALI; reports were made to the CDC from all 50 states, the District of Columbia, and two U.S. territories (Puerto Rico and the U.S. Virgin Islands).

Is THC in vaping fluid?

The focus of the outbreak has now turned to vaping products that contain THC, but it is important not to lose sight of the larger health issues around vaping. E-cigarette fluids have been shown to contain at least seven groups of potentially toxic compounds: nicotine, carbonyls, volatile organic compounds (such as benzene and toluene), particles, trace metal elements according to flavor, 8 bacterial endotoxins, and fungal glucans. 9 Two flavorants alone, diacetyl and 2,3-pentanediol, have been shown to perturb gene expression pathways related to cilia and cytoskeletal processes in normal human bronchial epithelial cells. 10

Can vitamin E cause lung injury?

Additional experimental studies in animals may provide information on whether exposure to vitamin E acetate alone can directly cause acute lung injury.

Does vitamin E oil cause edema?

Specifically, the severe inflammatory response and edema may be a result of the pyrolysis products (some of which are gases [e.g., ketene] and not easily measured in biologic samples) of vitamin E oil rather than the parent compound itself.

Does nicotine vaping cause lung disease?

As Layden et al. point out, the literature contains reports of acute lung disease — including acute eosinophilic pneumonia, respiratory bronchiolitis-associated interstitial lung disease, and hypersensitivity pneumonitis — that has also been associated with use of nicotine-containing liquids. 11-13 Since the industry has not been required by regulatory agencies to report all ingredients (nor their pyrolysis products), it would be imprudent to assume that patients with EVALI who report only nicotine vaping are underreporting THC use. Our default position as physicians is to believe our patients. The burden should be on the nicotine vaping companies to prove that their vaping fluids do not contain pulmonary toxicants capable of producing acute and chronic lung disorders. We need to heed the lesson from environmental public health regarding the precautionary principle that holds when a new product is developed that may have the potential for harm: it should be tested carefully for toxicity before being marketed widely. 14

Why is pulmonary edema so hard to breathe?

Overview. Pulmonary edema is a condition caused by excess fluid in the lungs. This fluid collects in the numerous air sacs in the lungs, making it difficult to breathe. In most cases, heart problems cause pulmonary edema. But fluid can collect in the lungs for other reasons, including pneumonia, exposure to certain toxins and medications, ...

What are the symptoms of pulmonary edema?

Sudden (acute) pulmonary edema signs and symptoms. Difficulty breathing (dyspnea) or extreme shortness of breath that worsens with activity or when lying down. A feeling of suffocating or drowning that worsens when lying down. A cough that produces frothy sputum that may be tinged with blood.

What is cardiogenic pulmonary edema?

Cardiogenic pulmonary edema is caused by increased pressures in the heart.

How long does it take for pulmonary edema to heal?

With treatment, most people with this type of pulmonary edema recover in about 24 hours.

Why does fluid build up in the lungs?

Most often, the fluid buildup in the lungs is due to a heart condition. If pulmonary edema is not heart related, it's called noncardiogenic pulmonary edema. Sometimes, pulmonary edema can be caused by both a heart problem and a non-heart problem.

What causes fluid to leak from the blood vessels to the lung tissues?

High-altitude pulmonary edema. In normal lungs, air sacs (alveoli) take in oxygen and release carbon dioxide. In high-altitude pulmonary edema (HAPE), it's theorized that vessels in the lungs constrict, causing increased pressure. This causes fluid to leak from the blood vessels to the lung tissues and eventually into the air sacs.

How high can you travel to get pulmonary edema?

People who travel to high-altitude locations above 8,000 feet (about 2,400 meters) are more likely to develop high-altitude pulmonary edema (HAPE). It usually affects those who do not first become acclimated to the elevation (which can take from a few days to a week or so).

What are the symptoms of a vaping patient?

The patient’s symptoms began with substernal, pleuritic chest pain. He then developed chills and vomiting (NBNB) of 7–8 episodes. The morning before presenting to the hospital, the patient went to an urgent care clinic for his worsening symptoms, but was then sent to the ED. His max temperature was 100 °F, blood pressure (BP) was 99/72 mmHg, HR of 116 BPM, respiratory rate (RR) of 19 breaths per minute (BRPM), oxygen saturation (SpO2) of 94% on ambient room air. Laboratory findings were notable for leukocytosis with a white blood cell count (WBC) of 24,900 cells per microliter, with 95.3% neutrophils, 1.6% lymphocytes, 2.1% monocytes, and 0.0% eosinophils. Procalcitonin was 0.45 ng/ml, LDH 400 ng/ml, D-Dimer 406.91 ng/mL, lactate negative, and lipase negative. CT chest notable for bilateral ground-glass opacities throughout both lungs and prominent lymph nodes.

How many cases of vaping induced pneumonitis are there?

One thousand eighty cases of vaping induced pneumonitis have been reported to the CDC as of October 1st, 2019. These cases come from 48 different state health departments and 1 U.S. territory. All patients had a history of e-cigarette use. The course of the disease process typically begins with pulmonary symptoms of nonproductive cough, pleuritic chest pain, and/or shortness of breath lasting over several days to weeks before the patient is hospitalized. All patients described in these reports had abnormal imaging that included infiltrates on chest radiograph and ground-glass opacities on chest CT scan. Gastrointestinal findings include nausea, vomiting, abdominal pain, and diarrhea have also been seen in these patients. Many patients, due to the nonspecific symptoms, received an initial diagnosis of infection and were treated with empiric antibiotics, which did not lead to improvement. One of the most severe symptoms that led to hospitalization was hypoxemia, which in some cases progressed to acute or subacute respiratory failure [ 2 ]. Patients in these cases needed multiple supplemental therapies, including supportive oxygen, endotracheal intubation, or even mechanical ventilation. The therapy that showed the most improvement in these patients was corticosteroids.

How many high school students use e-cigarettes?

The prevalence of ECs, or vaping, is increasing worldwide. Data shows increased use of e-cigarettes between 2011 to 2018 of 1.5 to 20.8% among high school students, an estimated increase from approximately 220,000 to 3.05 million high school students. Between 2017 and 2018, e-cigarette use was found to have increased 78% [ 1 ]. ECs are marketed as the “safe alternative” to smoking due to the belief that vaping could be a “harm reduction” alternative to smoking to the same degree as other Food and Drug Administration (FDA)-approved nicotine replacement therapies [ 2 ]. Vaping companies promote consumer attestations that ECs helped them quit smoking and improved their overall health [ 3 ]. These proclamations are controversial as there is sparse literature to show that EC users were more likely to quit smoking than regular cigarette users [ 4, 5 ]. There is a concern that ECs could increase worldwide nicotine dependence, especially among young adults who are enticed by the many flavors ECs offer [ 6 ]. The medical community is apprehensive of vaping and advises caution since limited scientific evidence is available to show their efficacy and safety [ 6 ]. We present three cases of pneumonitis seen at our small community hospital that further supports the harmful effects of ECs.

Patricia

Yep, I retain water too. I drink about 6 to 8 bottles of water a day. Water is very good for our bodies for all kinds of reasons but it should go out as fast as it goes in and I don't know why but since I started vaping I have noticed I am retaining a lot of fluid and I don't have any diuretics prescribed to help get rid of it.

TheRealKaty

HI I don't have any heart issues, however, I notice that I get swelling ANY time I vape my e-cig. I have a lot of food sensativities that result in puffiness and bloating, so I belive that my swelling comes from just general allergies to the additives and flavoring in the liquid.

What are the risks of vaping?

Other key points about vaping use include: 1 You can vape drugs other than nicotine, such as THC and CBD 2 It is possible to overdose on nicotine through vaping 3 Addiction to nicotine is also a serious side effect of vaping

How do you know if you're vaping too much?

How can you tell if someone is vaping too much? One study has shown that glycol and glycerin, two ingredients commonly used in vape juices, are upper airway irritants that can cause irritation of the throat and mouth as well as trigger a dry cough. But perhaps the biggest symptom of vaping too much is developing an addiction to nicotine, the chemical most commonly vaped.

Why is vaping good for you?

Vaping is a particularly powerful way of exposing your brain to nicotine because the juices used have such a concentrated amount of nicotine. The liquid nicotine used in e-cigarettes is absorbed far more quickly compared to nicotine from tobacco in regular cigarettes.

Why is vaping addictive?

Vaping nicotine is addictive because of the way it works in your brain. Nicotine enters the brain quickly to activate reward pathways and cause the release of endorphins, your body’s natural pain-killers. Vaping is a particularly powerful way of exposing your brain to nicotine because the juices used have such a concentrated amount of nicotine.

How many cases of pulmonary disease in 2019?

The Centers for Disease Control (CDC) released an emergency report about the risk of severe pulmonary disease among e-cigarette users. As of August 27, 2019, 215 confirmed cases of severe pulmonary disease associated with using e-cigarettes had been reported across the country.

Does a vaporizer have nicotine?

Cannabidiol (CBD) vaporizers don’t contain nicotine or THC, but they can still cause side effects. There is minimal research on the side effects of vaping CBD, but some general side effects of vaping CBD that have been reported include:

Can you vape with THC?

Stomach: Vomiting and nausea. Other key points about vaping use include: You can vape drugs other than nicotine, such as THC and CBD.

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